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The primary endpoint of a clinical trial is the endpoint for which the trial is powered. Secondary endpoints are additional endpoints, preferably also pre-specified, for which the trial may not be powered.
Endpoint (chemistry), the conclusion of a chemical reaction, particularly for titration Outcome measure , a measure used as an endpoint in research Clinical endpoint , in clinical research, a disease, symptom, or sign that constitutes one of the target outcomes of the trial or its participants
A surrogate endpoint of a clinical trial is a laboratory measurement or a physical sign used as a substitute for a clinically meaningful endpoint that measures directly how a patient feels, functions or survives. Changes induced by a therapy on a surrogate endpoint are expected to reflect changes in a clinically meaningful endpoint. [8]
Major adverse cardiovascular events (MACE, or major adverse cardiac events) is a composite endpoint frequently used in cardiovascular research. [1] [2] Despite widespread use of the term in clinical trials, the definitions of MACE can differ, which makes comparison of similar studies difficult. [3]
A drop of indicator solution is added to the titration at the start; when the color changes the endpoint has been reached, this is an approximation of the equivalence point. Conductance The conductivity of a solution depends on the ions that are present in it. During many titrations, the conductivity changes significantly.
In usual analytical chemistry practice, the term conductometry is used as a synonym of conductometric titration while the term conductimetry is used to describe non-titrative applications. [1] Conductometry is often applied to determine the total conductance of a solution or to analyze the end point of titrations that include ions. [2]
A network socket is a software structure within a network node of a computer network that serves as an endpoint for sending and receiving data across the network. The structure and properties of a socket are defined by an application programming interface (API) for the networking architecture.
A thesaurus (pl.: thesauri or thesauruses), sometimes called a synonym dictionary or dictionary of synonyms, is a reference work which arranges words by their meanings (or in simpler terms, a book where one can find different words with similar meanings to other words), [1] [2] sometimes as a hierarchy of broader and narrower terms, sometimes simply as lists of synonyms and antonyms.