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  2. Pain and pleasure - Wikipedia

    en.wikipedia.org/wiki/Pain_and_pleasure

    Activity in many parts of the brain is associated with pain perception. Some of the known parts for the ascending pathway include the thalamus, hypothalamus, midbrain, lentiform nucleus, somatosensory cortices, insular, prefrontal, anterior and parietal cingulum. [2] Then, there are also the descending pathways for the modulation of pain sensation.

  3. Endorphins - Wikipedia

    en.wikipedia.org/wiki/Endorphins

    Endorphins (contracted from endogenous morphine) [1] [2] [3] are peptides produced in the brain that block the perception of pain and increase feelings of wellbeing. They are produced and stored in the pituitary gland of the brain.

  4. Somatosensory system - Wikipedia

    en.wikipedia.org/wiki/Somatosensory_system

    Area S2 processes light touch, pain, visceral sensation, and tactile attention. S1 processes the remaining info (crude touch, pain, temperature). [13] [14] [15] BA7 integrates visual and proprioceptive info to locate objects in space. [16] [17] The insular cortex (insula) plays a role in the sense of bodily-ownership, bodily self-awareness, and ...

  5. Insular cortex - Wikipedia

    en.wikipedia.org/wiki/Insular_cortex

    Further, the insula is where a person imagines pain when looking at images of painful events while thinking about their happening to one's own body. [29] Those with irritable bowel syndrome have abnormal processing of visceral pain in the insular cortex related to dysfunctional inhibition of pain within the brain. [30]

  6. Periaqueductal gray - Wikipedia

    en.wikipedia.org/wiki/Periaqueductal_gray

    The periaqueductal gray (PAG), also known as the central gray, is a brain region that plays a critical role in autonomic function, motivated behavior and behavioural responses to threatening stimuli. [1] [2] PAG is also the primary control center for descending pain modulation. It has enkephalin-producing cells that suppress pain.

  7. Limbic system - Wikipedia

    en.wikipedia.org/wiki/Limbic_system

    The basal ganglia are a set of subcortical structures that direct intentional movements. The basal ganglia are located near the thalamus and hypothalamus. They receive input from the cerebral cortex, which sends outputs to the motor centers in the brain stem. A part of the basal ganglia called the striatum controls posture and movement.

  8. This Is What Happens to Your Brain When You Orgasm ... - AOL

    www.aol.com/entertainment/happens-brain-orgasm...

    The end result is that the brain’s pain inhibiting system is activated, thus reducing pain. But, more importantly, “the peptides themselves, when they’re released, give us a sense of well ...

  9. Gate control theory - Wikipedia

    en.wikipedia.org/wiki/Gate_control_theory

    Thus, the brain controls the perception of pain quite directly, and can be "trained" to turn off forms of pain that are not "useful". This understanding led Melzack to assert that pain is in the brain. [citation needed] Gate control theory influenced the development of mindfulness-based pain management (MBPM). [12]