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Mueller–Weiss syndrome, also known as Mueller–Weiss disease, is a rare [2] idiopathic degenerative disease of the adult navicular bone characterized by progressive collapse and fragmentation, leading to mid- and hindfoot pain and deformity.
The clinical presentation varies depending on the stage of the disease from mild swelling to severe swelling and moderate deformity. Inflammation, erythema, pain and increased skin temperature (3–7 degrees Celsius) around the joint may be noticeable on examination. X-rays may reveal bone resorption and degenerative changes in the joint.
Any part of the foot can be affected by diseases, with symptoms ranging from mild aches to more serious pain hindering one's ability to walk or bear weight. Most minor cases of foot pain can be responded to by home care treatments. However, when severe pain is present, medical attention is required as it is a disabling condition.
In the temporomandibular joint, subchondral sclerosis of the mandibular condyle has been described as an early change, condylar flattening as a feature of progressive osteoarthritis, and narrowing of the temporomandibular joint space as a late stage change. [14] A joint space of between 1.5 and 4 mm is regarded as normal. [15] Ankle osteoarthritis.
Degenerative disease is the result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time. [1] In neurodegenerative diseases, cells of the central nervous system stop working or die via neurodegeneration. An example of this is Alzheimer's disease. [2]
Eburnation is a degenerative process of bone commonly found in patients with osteoarthritis or non-union of fractures. Friction in the joint causes the reactive conversion of the sub-chondral bone to an ivory-like surface at the site of the cartilage erosion. [1] The word derives from Latin eburneus, which means "of ivory". [2]
Articular cartilage damage is often the cause of severe pain, swellings, strong barriers to mobility and severe restrictions to the patient's activities. Over the last decades, however, surgeons and biotech ventures [ who? ] have elaborated promising procedures [ which? ] that contribute to articular cartilage repair . [ 1 ]
A pre-operative image of a 22-year-old male with a very extreme case of Scheuermann's disease. Scheuermann's disease is a skeletal disorder. [3] It describes a condition where the vertebrae grow unevenly with respect to the sagittal plane; that is, the posterior angle is often greater than the anterior.