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  2. Bottom–up and top–down design - Wikipedia

    en.wikipedia.org/wiki/Bottom–up_and_topdown...

    Information flow top-down and bottom-up in leadership. In the fields of management and organization, the terms "top-down" and "bottom-up" are used to describe how decisions are made and/or how change is implemented. [17] A "top-down" approach is where an executive decision maker or other top person makes the decisions of how something should be ...

  3. Bottom-up - Wikipedia

    en.wikipedia.org/wiki/Bottom-up

    Bottom-up parsing, a computer science strategy; Bottom-up processing, in Pattern recognition (psychology) Bottom-up theories of galaxy formation and evolution; Bottom-up tree automaton, in data structures; Bottom-up integration testing, in software testing; Top-down and bottom-up design, strategies of information processing and knowledge ordering

  4. Top-down proteomics - Wikipedia

    en.wikipedia.org/wiki/Top-down_proteomics

    Top-down vs bottom-up proteomics. Top-down proteomics is a method of protein identification that either uses an ion trapping mass spectrometer to store an isolated protein ion for mass measurement and tandem mass spectrometry (MS/MS) analysis [1] [2] or other protein purification methods such as two-dimensional gel electrophoresis in conjunction with MS/MS. [3] Top-down proteomics is capable ...

  5. Hierarchical clustering - Wikipedia

    en.wikipedia.org/wiki/Hierarchical_clustering

    Agglomerative: This is a "bottom-up" approach: Each observation starts in its own cluster, and pairs of clusters are merged as one moves up the hierarchy. Divisive: This is a "top-down" approach: All observations start in one cluster, and splits are performed recursively as one moves down the hierarchy.

  6. Top-down - Wikipedia

    en.wikipedia.org/wiki/Top-down

    Top-down and bottom-up design of information ordering; Top-down parsing, a parsing strategy beginning at the highest level of the parse tree Top-down parsing language, an analytic formal grammar to study top-down parsers; Top-down perspective, a camera angle in computer and video games; Top-down shooter, a subgenre of video games

  7. Systems biology - Wikipedia

    en.wikipedia.org/wiki/Systems_biology

    In approaching a systems biology problem there are two main approaches. These are the top down and bottom up approach. The top down approach takes as much of the system into account as possible and relies largely on experimental results. The RNA-Seq technique is an example of an experimental top down approach. Conversely, the bottom up approach ...

  8. Grassroots - Wikipedia

    en.wikipedia.org/wiki/Grassroots

    There is an ongoing debate as to whether a bottom-up or top-down approach is better suited to address the problems facing communities. Top-down processing involves large-scale programs or high-level frameworks, often driven by governmental or international action.

  9. Bottom-up parsing - Wikipedia

    en.wikipedia.org/wiki/Bottom-up_parsing

    Bottom-up versus top-down [ edit ] The bottom-up name comes from the concept of a parse tree , in which the most detailed parts are at the bottom of the upside-down tree, and larger structures composed from them are in successively higher layers, until at the top or "root" of the tree a single unit describes the entire input stream.