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Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. [ 1 ] [ 13 ] [ 2 ] It has also been used off-label for certain other indications, like treatment of low blood pressure .
After an FDA advisory committee said the decongestant phenylephrine, an ingredient found in many oral cold and flu medications, is ineffective, experts weigh in on alternatives.
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness ).
NyQuil D contains pseudoephedrine, a decongestant that in some regions (such as the United States) is now placed behind the counters at pharmacy and other retail stores and must be requested by the customer. It contains the following active ingredients (15 mL is one tablespoon, half the recommended adult dose):
The leading decongestant used by millions of Americans looking for relief from a stuffy nose is no better than a dummy pill, according to government experts who reviewed the latest research on the ...
The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...
Extended usage of xylometazoline can result in decreased effectiveness or a buildup of tolerance against the drug. [12] The number of receptors decreases, and when the administration of the drug is ceased, chronic congestion can occur; this is called rhinitis medicamentosa , commonly referred to as rebound congestion.
Legal restrictions on pseudoephedrine have not reduced meth use, but they have driven people with colds or allergies toward substitutes that seem to be completely ineffective.