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Copy number variation (CNV) is a phenomenon in which sections of the genome are repeated and the number of repeats in the genome varies between individuals. [1] Copy number variation is a type of structural variation: specifically, it is a type of duplication or deletion event that affects a considerable number of base pairs. [2]
Copy number analysis is the process of analyzing data produced by a test for DNA copy number variation in an organism's sample. One application of such analysis is the detection of chromosomal copy number variation that may cause or may increase risks of various critical disorders.
Time period definitions use two standard table columns as the start and end of a named time period, with closed set-open set semantics. This provides compatibility with existing data models, application code, and tools
This type of aberration is also known as Copy Number Gains or Amplification. An HSR is one type of change in a chromosome 's structure which is frequently observed in the nucleus of human cancer cells .
Array CGH has proven to be a specific, sensitive, fast and high-throughput technique, with considerable advantages compared to other methods used for the analysis of DNA copy number changes making it more amenable to diagnostic applications. Using this method, copy number changes at a level of 5–10 kilobases of DNA sequences can be detected. [15]
Many biotechnology applications utilize mutated plasmids that replicate to high copy number. For example, pBR322 is a medium copy number plasmid (~20 copies/cell) from which several high copy number cloning vectors (>100 copies/cell) have been derived by mutagenesis, such as the well known pUC series. [1] This delivers the convenience of high ...
SQL was initially developed at IBM by Donald D. Chamberlin and Raymond F. Boyce after learning about the relational model from Edgar F. Codd [12] in the early 1970s. [13] This version, initially called SEQUEL (Structured English Query Language), was designed to manipulate and retrieve data stored in IBM's original quasirelational database management system, System R, which a group at IBM San ...
TIME: for time values (e.g. 15:51:36). TIME WITH TIME ZONE: the same as TIME, but including details about the time zone in question. TIMESTAMP: This is a DATE and a TIME put together in one variable (e.g. 2011-05-03 15:51:36.123456). TIMESTAMP WITH TIME ZONE: the same as TIMESTAMP, but including details about the time zone in question.