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Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia , [ 2 ] [ 3 ] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine . [ 4 ]
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Antibiotics with less reliable but occasional (depending on isolate and subspecies) activity: occasionally penicillins including penicillin, ampicillin and ampicillin-sulbactam, amoxicillin and amoxicillin-clavulnate, and piperacillin-tazobactam (not all vancomycin-resistant Enterococcus isolates are resistant to penicillin and ampicillin)
This has the effect of dosing a person who doesn't consent to take the drug. The United Nations Special Rapporteur On Torture has classified this as a human rights violation and cruel or inhuman treatment. [17] The first LAI antipsychotics (often referred to as simply "LAIs") were the typical antipsychotics fluphenazine and haloperidol. [18]
The effective dosage guideline for an antipsychotic is very closely related to its receptor residency time (i.e., where drugs like aripiprazole take several minutes or more to disassociate from a receptor while drugs like quetiapine and clozapine—with guideline dosages in the hundreds of milligrams—take under 30s) [25] [26] [27] and long ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 7 February 2025. Chemical compound Pharmaceutical compound Pimozide Clinical data Trade names Orap AHFS / Drugs.com Monograph MedlinePlus a686018 License data US FDA: Pimozide Pregnancy category AU: B1 Routes of administration Oral Drug class Typical antipsychotic ATC code N05AG02 (WHO) Legal status ...
Though the current (2007) guidelines dictate more restricted antibiotic use, many dentists [38] and dental patients [39] follow the 1997 guidelines instead, leading to overuse of antibiotics. [ 40 ] A study by Imperial College London in February 2017 found that of 20 online websites, 9 would provide antibiotics (illegally) without a ...