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Olanzapine is approved by the US FDA for: Treatment—in combination with fluoxetine—of depressive episodes associated with bipolar disorder (December 2003). [109] Long-term treatment of bipolar I disorder (January 2004). [110] [111] Long-term treatment—in combination with fluoxetine—of resistant depression (March 2009) [112]
Olanzapine/fluoxetine could produce a severe allergic reaction and should not be used if the patient has previously experienced an allergic reaction to either fluoxetine or olanzapine. [9] Olanzapine is correlated with an increase in blood sugar. Patients with diabetes, or those at risk for developing it, require careful monitoring. [9]
Olanzapine/samidorphan, sold under the brand name Lybalvi, is a fixed-dose combination medication for the treatment of schizophrenia and bipolar I disorder. [1] It contains olanzapine , an atypical antipsychotic , and samidorphan , an opioid antagonist .
The FDA hasn’t approved ketamine to treat bipolar disorder. However, it’s been used off-label to manage pain and depression since the 1970s and may have antidepressant and anti-suicidal ...
In 2005, the FDA issued an advisory warning of an increased risk of death when atypical antipsychotics are used in dementia. [47] In the subsequent 5 years, the use of atypical antipsychotics to treat dementia decreased by nearly 50%. [47] As of now, the only FDA-approved atypical antipsychotic for alzheimer-related dementia is brexpiprazole.
It is also approved for weight loss in those that are either obese or overweight with some weight-related illnesses Cymbalta ( duloxetine ) – an antidepressant of the serotonin-norepinephrine reuptake inhibitors class
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