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  2. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  3. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    Suppose a patient just started taking 100 mg of foosporin every day. On the first day, they'd have 100 mg in their system; their body would clear 10 mg, leaving 90 mg. On the second day, the patient would have 190 mg in total; their body would clear 19 mg, leaving 171 mg.

  4. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    For example, steady-state concentrations of drugs eliminated mostly by the kidney are usually greater in patients with kidney failure than they are in patients with normal kidney function receiving the same drug dosage. Population pharmacokinetics seeks to identify the measurable pathophysiologic factors and explain sources of variability that ...

  5. Dose (biochemistry) - Wikipedia

    en.wikipedia.org/wiki/Dose_(biochemistry)

    For example, if the desired total daily amount is 600 mg per day, they may decide a dosage plan that has one 200 mg dose taken three times a day, or one 300 mg dose taken twice a day, or a single 600 mg dose take once a day. Medication underdosing occurs commonly when physicians write prescriptions that are correct for a certain time, but fails ...

  6. Threshold dose - Wikipedia

    en.wikipedia.org/wiki/Threshold_dose

    Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]

  7. Dosimetry - Wikipedia

    en.wikipedia.org/wiki/Dosimetry

    Radiation dosimetry in the fields of health physics and radiation protection is the measurement, calculation and assessment of the ionizing radiation dose absorbed by an object, usually the human body. This applies both internally, due to ingested or inhaled radioactive substances, or externally due to irradiation by sources of radiation.

  8. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    One use is as a last line of opioid treatment for terminal cancer patients with intractable cancer pain. [20] A transdermal patch which delivers medication is applied to the skin. The patch is labelled with the time and date of administration as well as the administrator's initials. A medical professional applies nose drops.

  9. Dosage form - Wikipedia

    en.wikipedia.org/wiki/Dosage_form

    The term dosage form may also sometimes refer only to the pharmaceutical formulation of a drug product's constituent substances, without considering its final configuration as a consumable product (e.g., capsule, patch, etc.). Due to the somewhat ambiguous nature and overlap of these terms within the pharmaceutical industry, caution is ...