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Acanthocyte-like cells may be found in hypothyroidism, after splenectomy, and in myelodysplasia. [ 12 ] Acanthocytes should be distinguished from echinocytes , which are also called 'burr cells', which although crenated are dissimilar in that they have multiple, small, projecting spiculations at regular intervals on the cell membrane.
Echinocyte (from the Greek word echinos, meaning 'hedgehog' or 'sea urchin'), in human biology and medicine, refers to a form of red blood cell that has an abnormal cell membrane characterized by many small, evenly spaced thorny projections.
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Poikilocytosis may be diagnosed with a test called a blood smear.During a blood smear, a medical technologist/clinical lab scientist spreads a thin layer of blood on a microscope slide and stains the blood to help differentiate the cells.
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