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The cause of PML is a type of polyomavirus called the JC virus (JCV), after the initials of the person (John Cunningham) from whose tissue the virus was first successfully cultured. Publications indicate 39 [ 3 ] to 58% [ 4 ] of the general population are seropositive for antibodies to JCV, indicating current or previous infection with the virus.
Every year, about 1.3 million American women enter menopause—the stage of life when your estrogen levels diminish and your periods stop completely. It’s a natural part of aging and nothing to ...
“Menopause” refers to the point one year after your last menstrual flow—which you can’t know you’ve hit until 12 months have passed. Menopause is really more of a line you cross than a ...
In the years before and after menopause, the body undergoes many changes, leading to symptoms that may include hot flashes, emotional changes, and sleep disturbances. ... period and ends 12 months ...
Menopause, also known as the climacteric, is the time when menstrual periods permanently stop, marking the end of the reproductive stage for the female human. [1] [6] [7] It typically occurs between the ages of 45 and 55, although the exact timing can vary. [8]
Estradiol levels with rectal administration of estradiol in women after a single 1 mg dose 3 hours post-dose, with 0.5 mg/day 6 hours after the last dose, and with 1 mg/day 6 hours after the last dose. [261] [72] [242] [70] Estradiol has been assessed for use by rectal administration in a number of studies.