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This system of release is commonly referred to as glucose-stimulated insulin secretion (GSIS). [10] There are four key pieces to the triggering pathway of GSIS: GLUT2 dependent glucose uptake, glucose metabolism, KATP channel closure, and the opening of voltage gated calcium channels causing insulin granule fusion and exocytosis. [11] [12]
Endocrine glands are glands of the endocrine system that secrete their products, hormones, directly into interstitial spaces where they are absorbed into blood rather than through a duct. The major glands of the endocrine system include the pineal gland , pituitary gland , pancreas , ovaries , testes , thyroid gland , parathyroid gland ...
The endocrine system is a network of glands and organs located throughout the body. It is similar to the nervous system in that it plays a vital role in controlling and regulating many of the body's functions. Endocrine glands are ductless glands of the endocrine system that secrete their products, hormones, directly into the blood.
Endocrinology (from endocrine + -ology) is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones.It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep ...
This dual-origin structure and function are what make the pituitary gland a unique and critical component of the endocrine system, acting as a bridge between the nervous and endocrine systems. 5. Pituitary stem cells: stem cells are found in the pituitary [ 12 ] [ 13 ] which can differentiate into various types of hormone-producing cells in ...
The hypothalamus produces the hormones oxytocin and vasopressin in its endocrine cells (left). These are released at nerve endings in the posterior pituitary gland and then secreted into the systemic circulation. The hypothalamus releases tropic hormones into the hypophyseal portal system to the anterior pituitary (right).
The adrenal glands may not develop at all, or may be fused in the midline behind the aorta. [12] These are associated with other congenital abnormalities, such as failure of the kidneys to develop, or fused kidneys. [12] The gland may develop with a partial or complete absence of the cortex, or may develop in an unusual location. [12]
Relaxes smooth muscle of gut, blood vessels, and genitourinary system; increases water and electrolyte secretion from pancreas and gut; releases hormones from pancreas, gut, and hypothalamus Glucose-dependent insulinotropic: 4976: 42: Duodenum and jejunum