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The process of transcription is a major source of DNA damage, due to the formation of single-strand DNA intermediates that are vulnerable to damage. [53] The regulation of transcription by processes using base excision repair and/or topoisomerases to cut and remodel the genome also increases the vulnerability of DNA to damage. [53]
Several cell function specific transcription factor proteins (in 2018 Lambert et al. indicated there were about 1,600 transcription factors in a human cell [41]) generally bind to specific motifs on an enhancer [22] and a small combination of these enhancer-bound transcription factors, when brought close to a promoter by a DNA loop, govern the ...
On 12 August 2014 the Transcription Center website was launched to the public. [2] As well as transcribing, volunteers review the submitted work before it is sent for approval. [5] The final transcription is then checked by Smithsonian staff and once accepted, both the original images of the work and the transcription are kept on line. [6]
Eukaryotic Transcription. Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of transportable complementary RNA replica. [1] Gene transcription occurs in both eukaryotic and prokaryotic cells. Unlike prokaryotic RNA polymerase that initiates the transcription of all ...
Upstream transcription factors are proteins that bind somewhere upstream of the initiation site to stimulate or repress transcription. These are roughly synonymous with specific transcription factors , because they vary considerably depending on what recognition sequences are present in the proximity of the gene.
10 Best Remote Transcription Jobs That Pay Well. Caitlyn Moorhead. July 27, 2023 at 3:37 PM. Anchiy / Getty Images.
Several cell function-specific transcription factors (among the about 1,600 transcription factors in a human cell) [68] generally bind to specific motifs on an enhancer. [69] A small combination of these enhancer-bound transcription factors, when brought close to a promoter by a DNA loop, govern transcription level of the target gene.
Transcriptionists listen to videos and audio files and convert spoken words into written text. This work is necessary in a wide range of industries, including healthcare, legal, and marketing, to ...
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