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Pyoderma gangrenosum is a rare, inflammatory skin disease where painful pustules or nodules become ulcers that progressively grow. [3] Pyoderma gangrenosum is not infectious. [3] Treatments may include corticosteroids, ciclosporin, infliximab, or canakinumab. [2] The disease was identified in 1930.
Treatments directed at tumor necrosis factor (infliximab, etanercept) and interleukin-1 have shown a good response in resistant arthritis and pyoderma gangrenosum. [10] [11] [12] Other traditional immunosuppressant treatments for arthritis or pyoderma gangrenosum may also be used. [citation needed]
Type 2 diabetes can develop in dogs, although it is not as prevalent as type 1. [9] Because of this, there is no possibility the permanently damaged pancreatic beta cells could re-activate to engender a remission as may be possible with some feline diabetes cases, where the primary type of diabetes is type 2. [10] [11] [12] Gestational diabetes ...
A dog with degenerative myelopathy often stands with its legs close together and may not correct an unusual foot position due to a lack of conscious proprioception. Canine degenerative myelopathy, also known as chronic degenerative radiculomyelopathy, is an incurable, progressive disease of the canine spinal cord that is similar in many ways to amyotrophic lateral sclerosis (ALS).
The inflammation and ulceration that occurs as a result of pathergy in pyoderma gangrenosum often responds to systemic steroid therapy. The pathergy reaction is a unique feature of Behçet's disease and, according to the International Study Group for Behcet's Disease, is among the major criteria required for the diagnosis.
Bacterial diseases in dogs are usually not contagious from dog to dog; instead they are usually the result of wound colonization, opportunistic infections secondary to decreased resistance (often the result of viral infections), or secondary to other conditions (pyoderma secondary to skin allergies or pyometra secondary to cystic endometrial ...