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7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as kratom, have been used in herbal medicine since at least the 19th century. [5]
U-47700, also known as U4, pink heroin, pinky, and pink, is an opioid analgesic drug developed by a team at Upjohn in the 1970s [1] which has around 7.5 times the potency of morphine in animal models. [2] [3] [4] Physical Sample of U-47700 [5]
A Texas judge on Thursday ordered a New York doctor to pay more than $100,000 in penalties for prescribing abortion pills to a woman near Dallas, a ruling that could test “shield laws” in ...
Federal officials on Thursday approved a new type of pain pill designed to eliminate the risks of addiction and overdose associated with opioid medications like Vicodin and OxyContin.
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Ether extracts about 1–7% of the dried leaf mass. [27] Vachellia sieberiana, DMT, in the leaf [9] Acacia simplex, DMT and NMT, in the leaf, stem and trunk bark, 0.81% DMT in bark, MMT [9] [43] Vachellia tortilis, DMT, NMT, and other tryptamines [33] Acacia vestita, Tryptamine, in the leaf and stem, [9] but less than 0.02% total alkaloids [15]
Erowid was founded in April 1995 as a small business; their website appeared six months later. [5] The name "Erowid" was chosen to reflect the organization's stated philosophy of education. Using Proto-Indo-European linguistic roots, "Erowid" roughly translates into "Earth Wisdom" (*h₁er-, *weyd-). [3]