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  2. Faricimab - Wikipedia

    en.wikipedia.org/wiki/Faricimab

    Faricimab, sold under the brand name Vabysmo (/ v ə ˈ b aɪ z m oʊ / və-BYEZ-mow), is a monoclonal antibody used for the treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME).

  3. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  4. Brolucizumab - Wikipedia

    en.wikipedia.org/wiki/Brolucizumab

    Brolucizumab is approved by the US Food and Drug Administration (FDA) for use in ophthalmology. [7] [8]Brolucizumab successfully completed phase III development in wet age-related macular degeneration (AMD) meeting the primary efficacy endpoint of non-inferiority to aflibercept in mean change in best corrected visual acuity (BCVA) from baseline to week 48.

  5. FDA Approves First Injectable Eye Medicine For Vision Loss ...

    www.aol.com/news/fda-approves-first-injectable...

    The FDA has approved Genentech's, a unit of Roche Holdings AG (OTC: RHHBY), Vabysmo (faricimab-svoa) for wet, or neovascular, age-related macular degeneration (AMD) and diabetic macular edema (DME).

  6. Regeneron's Eylea could return to growth after nod to high ...

    www.aol.com/news/regenerons-eylea-could-return...

    A longer dosing gap for the drug could help Regeneron take on rival Roche's Vabysmo and also help soften the blow from incoming cheaper copycat drugs, analysts said. Shares of Regeneron rose 1.7% ...

  7. Roche shares fall on modest 2024 outlook - AOL

    www.aol.com/news/roche-forecasts-return-growth...

    LONDON/FRANKFURT (Reuters) -Roche shares fell more than 4% on Thursday as the market expressed disappointed with the company's more modest than expected 2024 outlook. Sales in 2023 rose 1% when ...

  8. Macular edema - Wikipedia

    en.wikipedia.org/wiki/Macular_edema

    The causes of macular edema are numerous and different causes may be inter-related. It is commonly associated with diabetes.Chronic or uncontrolled diabetes type 2 can affect peripheral blood vessels including those of the retina which may leak fluid, blood and occasionally fats into the retina causing it to swell.

  9. Ramucirumab - Wikipedia

    en.wikipedia.org/wiki/Ramucirumab

    The approval was based on the results of the RAINBOW trial, that compared ramucirumab plus paclitaxel or paclitaxel alone. [ 11 ] In December 2014, the FDA approved ramucirumab in combination with docetaxel for treatment of metastatic non-small-cell lung carcinoma (NSCLC) with disease progression during or after first-line platinum-containing ...