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2C-B (4-bromo-2,5-dimethoxyphenethylamine), also known as Nexus, is a synthetic psychedelic drug of the 2C family, mainly used as a recreational drug. [ 2 ] [ 1 ] [ 4 ] It was first synthesized by Alexander Shulgin in 1974 for use in psychotherapy .
2-Bromoanisole is an organobromide with the formula BrC 6 H 4 OCH 3. A colorless liquid, it is one of three isomers of bromoanisole, the others being 3-bromoanisole and 4-bromoanisole . It is a standard coupling partner in metal catalyzed coupling reactions.
2-Bromo-4,5-methylenedioxyamphetamine (6-Bromo-MDA) is a lesser-known psychedelic drug and a substituted amphetamine. It was first synthesized by Alexander Shulgin. In his book PiHKAL, the dose is listed as 350 mg and the duration unknown. [1] It produces stimulant effects but with no psychedelic or empathogenic action. [1]
The full name of the chemical is 2,5-dimethoxy-4-bromoamphetamine. DOB has a stereocenter and R -(−)-DOB is the eutomer . This is an important finding as it is suggestive that it is targeting different receptors relative to most other phenethylamines (e.g. MDMA ) where the R -isomer serves as the distomer .
2C-B-aminorex (2C-B-AR) is a recreational designer drug with psychedelic effects. It is a substituted aminorex derivative which was first identified in Sweden in June 2019. [1] Structurally, it is a hybrid of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) and aminorex. [2]
4-Bromo-2,5-dimethoxy-1-benzylpiperazine (2C-B-BZP) is a psychoactive drug and research chemical of the piperazine chemical class which has been sold as a "designer drug". [ 1 ] [ 2 ] It produces stimulant effects similar to those of benzylpiperazine (BZP).
4-Methylaminorex (4-MAR, 4-MAX) is a stimulant drug of the 2-amino-5-aryloxazoline group that was first synthesized in 1960 by McNeil Laboratories. [2] It is also known by its street name "U4Euh" ("Euphoria"). It is banned in many countries as a stimulant. 4-Methylaminorex has effects comparable to methamphetamine but with a longer duration.
[2] [7] [10] [11] [12] At low doses, such as 1 to 4 mg, DOM produces effects including stimulation, euphoria, enhanced self-awareness, and mild dose-dependent perceptual disturbances. [2] At higher doses, of above 5 to 7 mg, DOM produces psychedelic effects.