Ads
related to: high bilirubin after blood transfusion treatment for leukemia prognosis- Treatment Option
Visit The Physician Website To
Learn More About This Treatment.
- Clinical Trial Data
Physicians, Find Results And
Study Design Information.
- Dosing & Administration
Learn About Important Dosing
Considerations For This Rx.
- View Patient Profiles
Patients Experience Treatment
Intolerance & Suboptimal Responses
- $0 Co-Pay Information
Patients With Private Insurance
Could Save On Their Prescription.
- Support & Financial Info
HCPs, Connect Your Patients With
Savings & Support Resources.
- Treatment Option
Search results
Results From The WOW.Com Content Network
Extremely high levels of unconjugated bilirubin in plasma enables bilirubin to cross the blood-brain-barrier to reach the brain and central nervous system to impart damage. This is termed kernicterus, or bilirubin encephalopathy. Kernicterus is rare in adults but is prevalent in newborns with underdeveloped blood-brain barriers and lower ...
Treatment of the condition is specific to the cause of hemolysis, but intense phototherapy and exchange transfusion can be used to help the patient excrete accumulated bilirubin. [11] Complications related to hemolytic jaundice include hyperbilirubinemia and chronic bilirubin encephalopathy, which may be deadly without proper treatment. [12] [13]
Symptomatic treatment can be given by blood transfusion, if there is marked anemia. A positive Coombs test is a relative contraindication to transfuse the patient. In cold hemolytic anemia there is advantage in transfusing warmed blood. In severe immune-related hemolytic anemia, steroid therapy is sometimes necessary.
Transfusion hemosiderosis can cause permanent damage to tissues that may lead to death. [2] Tissue damage can remain even after chelation therapy. [2] Outcomes are usually worse in patients who require blood transfusions compared to those who can have alternative therapies. [2] Cardiomyopathy and cardiac arrhythmia are often a cause of death. [1]
The FAB criteria for diagnosis are as follows: [21] Monocyte count >1x10 9 /L; 0–19% blasts in bone marrow <5% blasts in peripheral blood; The FAB also arbitrarily categorises CMML into myelodysplastic-like and myeloproliferative-like groups. A white blood count of 13x10 9 is used as a cut-off to differentiate the two. [12]
Normal levels of bilirubin in blood are below 1.0 mg/dl (17 μmol/L), while levels over 2–3 mg/dl (34–51 μmol/L) typically result in jaundice. [4] [9] High blood bilirubin is divided into two types: unconjugated and conjugated bilirubin. [10] Causes of jaundice vary from relatively benign to potentially fatal. [10]
Ad
related to: high bilirubin after blood transfusion treatment for leukemia prognosis