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Chronic pyelonephritis causes persistent flank or abdominal pain, signs of infection (fever, unintentional weight loss, malaise, decreased appetite), lower urinary tract symptoms and blood in the urine. [10] Chronic pyelonephritis can in addition cause fever of unknown origin.
Pyelonephritis occurs between 20 and 30 times less frequently. [4] They are the most common cause of hospital-acquired infections accounting for approximately 40%. [115] Rates of asymptomatic bacteria in the urine increase with age from two to seven percent in women of child-bearing age to as high as 50% in elderly women in care homes. [42]
Nephritis represents the ninth-most-common cause of death among all women in the US (and the fifth leading cause among non-Hispanic black women). [19] Worldwide, the highest rates [clarification needed] of nephritis are 50–55% for African or Asian descent followed by Hispanic at 43% and Caucasian at 17%. [20]
Infective endocarditis - Infection that affects the inner lining of the heart (endocardium) and can potentially cause a thrombus to form on one or more heart valves and, if left untreated, can cause septic emboli that can have many systemic effects, including deposition into the glomerulus, causing glomerulonephritis and nephritic syndrome. [25]
About 150 million people develop a urinary tract infection in a given year. [5] They are more common in women than men. [3] Up to 10% of women have a urinary tract infection in a given year, and half of women have at least one infection at some point in their lifetime.
Symptomatic bacteriuria is bacteriuria with the accompanying symptoms of a urinary tract infection (such as frequent urination, painful urination, fever, back pain, abdominal pain and blood in the urine) and includes pyelonephritis or cystitis. [11] The most common cause of urinary tract infections is Escherichia coli. [citation needed]