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  2. Griffith's experiment - Wikipedia

    en.wikipedia.org/wiki/Griffith's_experiment

    Griffith's experiment, [1] performed by Frederick Griffith and reported in 1928, [2] was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation. [3][4] Griffith's findings were followed by research in the late 1930s and early 40s that isolated DNA as the material ...

  3. Genetic transformation - Wikipedia

    en.wikipedia.org/wiki/Genetic_transformation

    This process of the second bacterial cell taking up new genetic material is called transformation. In molecular biology and genetics, transformation is the genetic alteration of a cell resulting from the direct uptake and incorporation of exogenous genetic material from its surroundings through the cell membrane (s).

  4. Genetic engineering - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering

    t. e. Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms.

  5. Horizontal gene transfer - Wikipedia

    en.wikipedia.org/wiki/Horizontal_gene_transfer

    Transformation is often used in laboratories to insert novel genes into bacteria for experiments or for industrial or medical applications. See also molecular biology and biotechnology. [citation needed] Transduction, the process in which bacterial DNA is moved from one bacterium to another by a virus (a bacteriophage, or phage). [41]

  6. Genetic recombination - Wikipedia

    en.wikipedia.org/wiki/Genetic_recombination

    Genetic recombination. A model of meiotic recombination, initiated by a double-strand break or gap, followed by pairing with an homologous chromosome and strand invasion to initiate the recombinational repair process. Repair of the gap can lead to crossover (CO) or non-crossover (NCO) of the flanking regions.

  7. Genetically modified organism - Wikipedia

    en.wikipedia.org/wiki/Genetically_modified_organism

    Mammals are the best model organisms for humans. Livestock is modified with the intention of improving economically important traits such as growth rate, quality of meat, milk composition, disease resistance, and survival. Genetically modified fish are used for scientific research, as pets, and as a food source.

  8. List of research methods in biology - Wikipedia

    en.wikipedia.org/wiki/List_of_research_methods...

    Used to automate the DNA sequencing process. Genetics, Molecular biology. Enzyme-linked immunosorbent assay (ELISA) Used to detect the presence of a ligand (commonly a protein) in a liquid sample using antibodies directed against the protein to be measure. Biochemistry, Molecular biology. Gene knockout.

  9. Transformation efficiency - Wikipedia

    en.wikipedia.org/wiki/Transformation_efficiency

    In molecular biology, transformation efficiency is a crucial parameter, it is used to evaluate the ability of different methods to introduce plasmid DNA into cells and to compare the efficiency of different plasmid, vectors and host cells. This efficiency can be affected by a number of factors, including the method used for introducing the DNA ...

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