Search results
Results From The WOW.Com Content Network
It is estimated that approximately 2-3% of people aged 52-89 years old have ocular hypertension of 25 mmHg and higher, and 3.5% of people 49 years and older have ocular hypertension of 21 mmHg and higher. [4] [5] Elevated intraocular pressure is an important risk factor and symptom of glaucoma. Accordingly, most individuals with consistently ...
Dorzolamide is used to lower excessive intraocular pressure in open-angle glaucoma and ocular hypertension.This drug is able to cross the cornea, reach the ciliary body of the eye, and produce systemic effects on the carbonic anhydrase enzyme within the eye.
The most important factor that must be taken into account when designing any type of drug delivery device, and specifically ocular devices, is the release rate of a drug. As discussed previously, the deliver rate and kinetics associated with drugs to the eye can reach levels that are toxic to the eye or could even cause undesirable side effects.
Ocular hypertension (OHT) is defined by intraocular pressure being higher than normal, in the absence of optic nerve damage or visual field loss. [13] [14] Ocular hypotension, hypotony, or ocular hypotony, is typically defined as intraocular pressure equal to or less than 5 mmHg.
Intravitreal injection was first mentioned in a study in 1911, in which the injection of air was used to repair a detached retina. [6] [7] [8] There were also investigations evaluating intravitreal antibiotics injection using sulfanilamide and penicillin to treat endophthalmitis in the 1940s, yet due to the inconsistency of results and safety concerns, this form of drug delivery was only for ...
Improvement to cognitive performance caused by exercise could last for 24 hours, a new study shows. Scientists also linked getting 6 or more hours of sleep to better memory test scores the next day.
Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...
Sleep apnea is a condition characterized by repeated interruptions in breathing during sleep, significantly affecting the flow of blood through the brain's blood vessels. These interruptions cause intermittent hypoxia, leading to vascular changes such as the constriction of cerebral blood vessels, thereby impacting overall brain blood flow.