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Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. [4] Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth.
Neurophysin I is the carrier protein for oxytocin. It is produced in the cell bodies of the paraventricular and supraoptic nuclei and transported to its site of release in the axon terminals of the posterior pituitary.
The posterior pituitary consists mainly of neuronal projections of magnocellular neurosecretory cells extending from the supraoptic and paraventricular nuclei of the hypothalamus. These axons store and release neurohypophysial hormones oxytocin and vasopressin into the neurohypophyseal capillaries, from there they get into the systemic ...
As for the orgasm connection, oxytocin is produced in the hypothalamus (i.e., the control center of the brain), which is yet another region activated—both in the posterior and anterior—during ...
The magnocellular cells in the PVN elaborate and secrete two peptide hormones: oxytocin and vasopressin. These hormones are packaged into large vesicles, which are then transported down the unmyelinated axons of the cells and released from neurosecretory nerve terminals residing in the posterior pituitary gland. [citation needed]
The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. [4] [5] In humans, the oxytocin receptor is encoded by the OXTR gene [6] [7] which has been localized to human chromosome 3p25. [8] Evolutionary tree of the oxytocin, vasotocin, mesotocin and isotocin receptors and ...
Most of the circulating oxytocin and vasopressin hormones are synthesized in magnocellular neurosecretory cells of the supraoptic nucleus and paraventricular nucleus of the hypothalamus. They are then transported in neurosecretory granules along axons within the hypothalamo-neurohypophysial tract by axoplasmic flow to axon terminals forming the ...
Specialized cells from the hypothalamus, known as pituicytes, migrate to the posterior pituitary, where they help store and release hormones such as oxytocin and vasopressin. 3. Hormone Production and Functional Maturity By around the 12th to 16th week of gestation, the anterior pituitary begins producing hormones like growth hormone (GH ...