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Salicylate poisoning, also known as aspirin poisoning, is the acute or chronic poisoning with a salicylate such as aspirin. [1] The classic symptoms are ringing in the ears, nausea, abdominal pain, and a fast breathing rate. [1] Early on, these may be subtle, while larger doses may result in fever.
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. It has been recognized since the 19th century. [1]
Studies have proven that high-dose usage of aspirin can be associated with ototoxicity, manifesting reversible hearing loss and tinnitus. [20] The underlying mechanism is associated with a change in isolated cochlear outer hair cells (OHCs). Due to the COX inhibition, there is an increasing amount of leukotrienes in the inner ear. This ...
According to EveryDayHealth.com, Tinnitus can be a side effect of certain medications -- including antibiotics, non-steroidal anti-inflammatory drugs, cancer drugs, and even aspirin when taken in ...
3. Your ears are plugged up. Blockages like ear wax (or, in very rare cases, a tumor) could cause ringing in your ears due to pressure on the nerves that run through your ear canal. You might also ...
An important salicylate drug is aspirin, which has a long history. Aspirin intolerance was widely known by 1975, when the understanding began to emerge that it is an adverse drug reaction, not an allergy. [6] [7]
Since the inner ear is not directly accessible to instruments, identification is by patient report of the symptoms and audiometric testing. Of those who present to their doctor with sensorineural hearing loss, 90% report having diminished hearing, 57% report having a plugged feeling in ear, and 49% report having ringing in ear ().
Like other medications for the treatment of (ED), Cialis — and its generic version, tadalafil — can cause adverse effects at first. Fortunately, most tadalafil side effects are mild and ...