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Silibinin (), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others.
Chronic liver dysfunction [3] [19] Kratom: Mitragyna speciosa: Hepatotoxicity [20] [19] Liquorice root Glycyrrhiza glabra: Hypokalemia, hypertension, arrhythmias, edema [5] Lobelia: asthma weed, pukeweed, vomit wort Lobelia inflata: Toxicity, rapid heartbeat, hypotension, coma, death [4] Milk thistle: Marian thistle Silybum marianum: Mild ...
Milk thistle: It has been used for thousands of years for a variety of medicinal purposes, in particular liver problems. [142] Stachytarpheta cayennensis: Blue snakeweed Extracts of the plant are used to ease the symptoms of malaria. The boiled juice or a tea made from the leaves or the whole plant is taken to relieve fever and other symptoms.
Milk thistle is believed to give some remedy for liver diseases (e.g. viral hepatitis) and the extract, silymarin, is used in medicine. Mild gastrointestinal distress is the most common adverse event reported for milk thistle. The incidence is the same as for placebo. [10] A laxative effect for milk thistle has also been reported infrequently. [11]
Flavonolignans identified in Silybum marianum (milk thistle) silymarin complex include silibinin, silychristin, silydianin, dehydrosilybin, deoxysilycistin, deoxysilydianin, silandrin, silybinome, silyhermin and neosilyhermin and can be produced in vitro. [1] Silibinin is found in the roots of S. marianum [2] while silyamandin [3] can be found ...
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