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Silibinin (), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others.
Milk thistle is believed to give some remedy for liver diseases (e.g. viral hepatitis) and the extract, silymarin, is used in medicine. Mild gastrointestinal distress is the most common adverse event reported for milk thistle. The incidence is the same as for placebo. [10] A laxative effect for milk thistle has also been reported infrequently. [11]
Chronic liver dysfunction [3] [19] Kratom: Mitragyna speciosa: Hepatotoxicity [20] [19] Liquorice root Glycyrrhiza glabra: Hypokalemia, hypertension, arrhythmias, edema [5] Lobelia: asthma weed, pukeweed, vomit wort Lobelia inflata: Toxicity, rapid heartbeat, hypotension, coma, death [4] Milk thistle: Marian thistle Silybum marianum: Mild ...
Silybum marianum is a species of thistle.It has various common names including milk thistle, [1] blessed milkthistle, [2] Marian thistle, Mary thistle, Saint Mary's thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle (not to be confused with Onopordum acanthium or Cirsium vulgare).
Blessed thistle: Used during the Middle Ages to treat bubonic plague. In modern times, herbal teas made from blessed thistle are used for loss of appetite, indigestion and other purposes. [50] Crataegus monogyna and Crataegus laevigata: Hawthorn: Fruit has been used for centuries purportedly for heart disease, digestive and kidney related ...
Silychristin (also known as silichristin) is a natural product and one of the constituents of silymarin, the standardized, active extract of the fruit of milk thistle, Silybum marianum. [ 1 ] [ 2 ] It is the second most abundant constituent in silymarin, after silybin . [ 3 ]
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