Search results
Results From The WOW.Com Content Network
Aldehyde dehydrogenase is a polymorphic enzyme [3] responsible for the oxidation of aldehydes to carboxylic acids. [3] There are three different classes of these enzymes in mammals: class 1 (low K m, cytosolic), class 2 (low K m, mitochondrial), and class 3 (high K m, such as those expressed in tumors, stomach, and cornea). In all three classes ...
This protein belongs to the aldehyde dehydrogenases family of proteins and is a member of the ALDH1 subfamily (including ALDH1A2, ALDH1A3, ALDH1B1, ALDH2). Aldehyde dehydrogenase isozymes are NAD(P)-dependent dehydrogenases that catalyze the oxidation of an aldehyde into the corresponding carboxylic acid while reducing NAD+ or NADP+.
In enzymology, an aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) is an enzyme that catalyzes the chemical reaction. an aldehyde + NAD + + H 2 O an acid + NADH + H + The 3 substrates of this enzyme are aldehyde, NAD +, and H 2 O, whereas its 3 products are acid, NADH, and H +. This enzyme belongs to the family of oxidoreductases, specifically
Stoichiometric equation representing the metabolism of an aldehyde substrate by ALDH3A1 using NADP+ as a cofactor. Electronic excitations of alkene and aromatic functional groups allow certain nucleic acids, proteins, fatty acids and organic molecules to absorb ultraviolet radiation (UVR).
Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene. [5] [6] This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities.
The systematic name of this enzyme class is aldehyde:NAD(P)+ oxidoreductase. Other names in common use include aldehyde dehydrogenase [NAD(P)+] , and ALDH . This enzyme participates in 5 metabolic pathways : glycolysis / gluconeogenesis , histidine metabolism , tyrosine metabolism , phenylalanine metabolism , and metabolism of xenobiotics by ...
220 56847 Ensembl ENSG00000184254 ENSMUSG00000015134 UniProt P47895 Q9JHW9 RefSeq (mRNA) NM_001293815 NM_000693 NM_001037224 NM_053080 RefSeq (protein) NP_000684 NP_001280744 NP_444310 Location (UCSC) Chr 15: 100.88 – 100.92 Mb Chr 7: 66.04 – 66.08 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Aldehyde dehydrogenase 1 family, member A3 (ALDH1a3), also known as retinaldehyde ...
Iron-binding proteins are carrier proteins and metalloproteins that are important in iron metabolism [1] and the immune response. [2] [3] Iron is required for life.Iron-dependent enzymes catalyze a variety of biochemical reactions and can be divided into three broad classes depending on the structure of their active site: non-heme mono-iron, non-heme diiron , or heme centers. [4]