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Tenosynovial giant cell tumor (TGCT) is a non-malignant tumor defined histologically as inclusions of “osteoclast-like” multinucleated giant cells, hemosiderin, and macrophages. [1] This histology can present one of 2 clinically distinct ways. TGCT tumors often develop from the lining of joints (also known as synovial tissue).
Giant-cell tumor of the tendon sheath, also known as giant-cell synovioma, localized nodular tenosynovitis and localized tenosynovial giant cell tumor or TGCT [1] is a firm lesion, measuring 1 to 3 cm in diameter, and is most commonly attached to the tendons of the fingers, hands, and wrists, with a predilection for the flexor surfaces.
Villonodular synovitis is a type of synovial swelling.. Types include: Pigmented villonodular synovitis; Giant cell tumor of the tendon sheath; Though they have very different names, they have the same histology, and stain positive for CD68, HAM56, and vimentin. [1]
The U.S. Food and Drug Administration on Friday approved Daiichi Sankyo Co Ltd's treatment for adult patients with a type of rare, non-cancerous tumor affecting joints and limbs. The decision ...
Localized fibrous tumor; M8815/3 Solitary fibrous tumor, malignant M8820/0 Elastofibroma M8821/1 Aggressive fibromatosis ... M9252/0 Tenosynovial giant cell tumor
A localized cancer that has not extended beyond the margins of the organ involved can also be described as localized disease, while cancers that extend into other tissues are described as invasive. Tumors that are non-hematologic in origin but extend into the bloodstream or lymphatic system are known as metastatic.
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