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Phosphorus occurs in amounts of about 2/3 of calcium, and makes up about 1% of a person's body weight. [10] The other major minerals (potassium, sodium, chlorine, sulfur and magnesium) make up only about 0.85% of the weight of the body. Together these eleven chemical elements (H, C, N, O, Ca, P, K, Na, Cl, S, Mg) make up 99.85% of the body.
Examples include phosphatidylinositol (4,5)-bisphosphate (PIP 2), that can be split by the enzyme phospholipase C into inositol triphosphate (IP 3) and diacylglycerol (DAG), which both carry out the functions of the G q type of G protein in response to various stimuli and intervene in various processes from long term depression in neurons [18 ...
Phosphorus and sulfur are also common essential elements, essential to the structure of nucleic acids and amino acids, respectively. Chlorine, potassium, magnesium, calcium and phosphorus have important roles due to their ready ionization and utility in regulating membrane activity and osmotic potential. [2]
Parts-per-million cube of relative abundance by mass of elements in an average adult human body down to 1 ppm. About 99% of the mass of the human body is made up of six elements: oxygen, carbon, hydrogen, nitrogen, calcium, and phosphorus. Only about 0.85% is composed of another five elements: potassium, sulfur, sodium, chlorine, and magnesium ...
Phosphorus is classified as a pnictogen, together with nitrogen, arsenic, antimony, bismuth, and moscovium. Phosphorus is an element essential to sustaining life largely through phosphates, compounds containing the phosphate ion, PO 4 3−. Phosphates are a component of DNA, RNA, ATP, and phospholipids, complex compounds fundamental to cells.
Phosphorus is contained in phospholipids, a class of lipids that are a major component of all cell membranes, as they can form lipid bilayers, which keep ions, proteins, and other molecules where they are needed for cell function, and prevent them from diffusing into areas where they should not be.
Phosphatidylserine (PS) is the major acidic phospholipid class that accounts for 13–15% of the phospholipids in the human cerebral cortex. [7] In the plasma membrane, PS is localized exclusively in the cytoplasmic leaflet where it forms part of protein docking sites necessary for the activation of several key signaling pathways.
Phosphorus, required component of bones; essential for energy processing. [71] Approximately 80% is found in the inorganic portion of bones and teeth. Phosphorus is a component of every cell, as well as important metabolites, including DNA, RNA, ATP, and phospholipids. Also important in pH regulation.