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In biology, homeostasis (British also homoeostasis; / h ɒ m i oʊ ˈ s t eɪ s ɪ s,-m i ə-/ hoh-mee-oh-STAY-sis) is the state of steady internal physical and chemical conditions maintained by living systems. [1]
Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism . [ 1 ]
In biochemistry, steady state refers to the maintenance of constant internal concentrations of molecules and ions in the cells and organs of living systems. [1] Living organisms remain at a dynamic steady state where their internal composition at both cellular and gross levels are relatively constant, but different from equilibrium concentrations. [1]
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The internal environment (or milieu intérieur in French; French pronunciation: [mi.ljø ɛ̃.te.ʁjœʁ]) was a concept developed by Claude Bernard, [1] [2] a French physiologist in the 19th century, to describe the interstitial fluid and its physiological capacity to ensure protective stability for the tissues and organs of multicellular organisms.
The plasma total calcium concentration is in the range of 2.2–2.6 mmol/L (9–10.5 mg/dL), and the normal ionized calcium is 1.3–1.5 mmol/L (4.5–5.6 mg/dL). [4] The amount of total calcium in the blood varies with the level of plasma albumin, the most abundant protein in plasma, and therefore the main carrier of protein-bound calcium in the blood.
Developmental homeostasis is a process in which animals develop more or less normally, despite defective genes and deficient environments. [1] It is an organism's ability to overcome certain circumstances in order to develop normally. This can be a circumstance that interferes with either a physical or mental trait.
Fluid balance is an aspect of the homeostasis of organisms in which the amount of water in the organism needs to be controlled, via osmoregulation and behavior, such that the concentrations of electrolytes (salts in solution) in the various body fluids are kept within healthy ranges.