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Memantine, sold under the brand name Namenda among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. [10] [11] [8] It is taken by mouth. [10] [8] Common side effects include headache, constipation, sleepiness, and dizziness. [10] [11] Severe side effects may include blood clots, psychosis, and heart ...
Memantine is sold as Namenda, although a version that combines memantine and donepezil (a cholinesterase inhibitor) is also available (Namzaric). Namenda may cause headaches, dizziness, agitation ...
Like memantine, nitromemantine is a low-affinity voltage-dependent uncompetitive antagonist at glutamatergic NMDA receptors, however nitromemantine selectively inhibits extrasynaptic NMDA receptors while sparing normal physiological synaptic NMDA receptor activity, resulting in less side effects and a greater neuroprotective action, as well as stimulating regrowth of synapses with prolonged ...
Memantine (Namenda) - treats Dementia and Alzheimer's. N. Neurontin – an anticonvulsant which is sometimes used as a mood stabilizer, anti-anxiety agent or to ...
Researchers discovered that amantadine and memantine bind to and act as agonists of the σ 1 receptor (K i = 7.44 μM and 2.60 μM, respectively) and that activation of the σ 1 receptor is involved in the central dopaminergic effects of amantadine at therapeutically relevant concentrations; the authors of the study stated that this could also ...
“Clinicians are advised to discuss benefits, side effects, withdrawal effects and address any concerns about taking or stopping medication. Patients should be advised that antidepressant ...
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