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Aphidicolin is a tetracyclic diterpene antibiotic isolated from the fungus Cephalosporum aphidicola with antiviral and antimitotic properties.
Disfunction in the LRP2-mediated endocytic trafficking and endocytic capacity in the proximal tubule can result in low molecular weight proteinuria, which is a hallmark of many diseases. [13] Mutations in the LRP2 gene are associated with Donnai-Barrow syndrome. [16]
Based on one definition, a drug-like molecule has a logarithm of partition coefficient (log P) between −0.4 and 5.6, molecular weight 160–480 g/mol, molar refractivity of 40–130, which is related to the volume and molecular weight of the molecule and has 20–70 atoms. [5]
SOD1 binds copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide.
One theory to explain antidepressant-related weight gain is that psychotropic medications such as antidepressants can affect neurotransmitters involved in eating behavior, causing an increase in ...
A commission proposed a new definition of obesity focused on how excess fat affects the body, rather than assessing body mass index, that could change clinical care. ... You can input weight and ...
Weight gain is an increase in body weight. This can involve an increase in muscle mass , fat deposits , excess fluids such as water or other factors. Weight gain can be a symptom of a serious medical condition.
A new Clean Label Project report suggests some protein powders contain heavy metals lead and cadmium. See which ones are safe here, plus what an expert advises.