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Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis) starts with the oxidation of l -tyrosine to l-dopa by the enzyme tyrosine hydroxylase , then to l -dopaquinone and dopachrome , which forms melanin.
Melanin (/ ˈ m ɛ l ə n ɪ n / ⓘ; from Ancient Greek μέλας (mélas) 'black, dark') is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. [1] Melanin pigments are produced in a specialized group of cells known as melanocytes.
A study in Sweden [2] showed that 21.5% of smokers and 3% of nonsmokers (genetic pigmentation or unknown cause) had lesions that could be classified as an oral melanin pigmentation. A gingival melanin index in 4 degrees was established. [5] Already with a consumption of 1-3 cigarettes a day 9.3% of all 20.333 examined showed a smoker's melanosis.
As an organ of the body, the lip can be a focus of disease or show symptoms of a disease: One of the most frequent changes of the lips is a blue coloring due to cyanosis; the blood contains less oxygen and thus has a dark red to blue color, which shows through the thin skin. Cyanosis is the reason why corpses sometimes have blue lips.
[19] [20] [21] It involves controlled application of cooling within the temperature range of −11 to +5 °C (+12.2 to +41 °F) for the localized reduction of fat deposits, intended to reshape the contours of the body. [19] [20] The degree of exposure to cooling causes cell death of subcutaneous fat tissue, without apparent damage to the ...
Cryotherapy damages the tissue by freezing its internal components – thereby jeopardising the cells' optimum temperature; leading to denaturation of enzymes and proteins required for cell function. Minimum temperature needed for cell damage is cell specific, and melanocytes are very sensitive to low temperatures at −4 °C to −7 °C where ...
In cell biology, a lymphokine-activated killer cell (also known as a LAK cell) is a white blood cell, consisting mostly of natural killer, natural killer T, and T cells that has been stimulated to kill tumor cells, but because of the function in which they activate, and the cells they can successfully target, they are classified as different than the classical natural killer and T lymphocyte ...
Dark therapy is the practice of keeping people in complete darkness for extended periods of time in an attempt to treat psychological conditions. The human body produces the melatonin hormone, which is responsible for supporting the circadian rhythms. Darkness seems to help keep these circadian rhythms stable. [1]