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Aggravation (or exacerbation) of lupus has been estimated to occur in about 20-30% pregnancies where the mother has lupus. [2] Increased disease activity of lupus is expected during pregnancy because of increased levels of estrogen, prolactin, and certain cytokines. [2] However, a long time of remission before pregnancy decreases the risk of ...
Lupus anticoagulant. Lupus anticoagulant is an immunoglobulin [1] that binds to phospholipids and proteins associated with the cell membrane. Its name is a partial misnomer, as it is actually a prothrombotic antibody in vivo. The name derives from their properties in vitro, as these antibodies increase coagulation times in laboratory tests such ...
2–7 per 10,000 [2] Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [1] Common symptoms include painful and swollen joints, fever, chest pain, hair ...
Lupus is a chronic autoimmune disease that causes inflammation throughout the body. The immune system targets various organs and tissues, including the joints, heart, skin, kidneys, blood, lungs ...
In blood samples of people with lupus, the researchers also tested the effects of adding a small molecule that activates the aryl hydrocarbon receptor. They found that it limited the accumulation ...
Libman–Sacks endocarditis involves formation of cardiac lesions that may take the form of vegetations or thickening of the valvular leaflets. [4][2] The vegetations are small and formed from strands of fibrin, neutrophils, lymphocytes, and histiocytes. [5] Vegetations are most often small-to-moderate in size (up to 10 mm), [4] but may ...
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