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Allicin is unstable and quickly changes into a series of other sulfur-containing compounds such as diallyl disulfide. [3] Allicin is an antifeedant, i.e. the defense mechanism against attacks by pests on the garlic plant. [4] Allicin is an oily, slightly yellow liquid that gives garlic its distinctive odor. It is a thioester of sulfenic acid.
Staphylococcus aureus. Colorized scanning electron micrograph of a human neutrophil ingesting MRSA. Methicillin-resistant Staphylococcus aureus (MRSA) is a group of gram-positive bacteria that are genetically distinct from other strains of Staphylococcus aureus. MRSA is responsible for several difficult-to-treat infections in humans.
It is used to treat urinary tract infections, methicillin-resistant Staphylococcus aureus (MRSA) skin infections, travelers' diarrhea, respiratory tract infections, and cholera, among others. [ 2 ] [ 7 ] It is used both to treat and prevent pneumocystis pneumonia and toxoplasmosis in people with HIV/AIDS and other causes of immunosuppression. [ 2 ]
Allicin is being studied for treatment of MRSA: Ref #13 is a review published in Trends in Food Science & Technology journal. Ref #14 is news in Oncology Times Journal. Both of the above are discussing the 2004 Cutler in vivo allicin study published in British Journal of Biomedical Science journal.
Vinyldithiin. Vinyldithiins, more precisely named 3-vinyl-4 H -1,2-dithiin and 2-vinyl-4 H -1,3-dithiin, are organosulfur phytochemicals formed in the breakdown of allicin from crushed garlic (Allium sativum). Vinyldithiins are Diels-Alder dimers of thioacrolein, H 2 C=CHCH=S, formed in turn by decomposition of allicin. [1]
Fusidic acid, sold under the brand name Fucidin among others, is a steroid antibiotic that is often used topically in creams or ointments and eyedrops but may also be given systemically as tablets or injections. As of October 2008, the global problem of advancing antimicrobial resistance has led to a renewed interest in its use.
The WHO defines antimicrobial resistance as a microorganism's resistance to an antimicrobial drug that was once able to treat an infection by that microorganism. [ 2 ] A person cannot become resistant to antibiotics. Resistance is a property of the microbe, not a person or other organism infected by a microbe. [ 33 ]
Antimicrobial spectrum. A simplified diagram showing common disease-causing bacteria and the antibiotics which act against them. The antimicrobial spectrum of an antibiotic means the range of microorganisms it can kill or inhibit. Antibiotics can be divided into broad-spectrum antibiotics, extended-spectrum antibiotics and narrow-spectrum ...