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  2. Large granular lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Large_granular_lymphocytic...

    Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. [1] It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL).

  3. Aggressive NK-cell leukemia - Wikipedia

    en.wikipedia.org/wiki/Aggressive_NK-cell_leukemia

    Patients usually present with constitutional symptoms (malaise, weight loss, fatigue), and hepatosplenomegaly is commonly found on physical exam. Lymphadenopathy is also found to a lesser extent. Due to the aggressive nature of the disease, patients may initially present at a more advanced stage, with coagulopathies , hemophagocytic syndrome ...

  4. Lymphoid leukemia - Wikipedia

    en.wikipedia.org/wiki/Lymphoid_leukemia

    Lymphoid leukemias are a group of leukemias affecting circulating lymphocytes, a type of white blood cell.The lymphocytic leukemias are closely related to lymphomas of the lymphocytes, to the point that some of them are unitary disease entities that can be called by either name (for example, adult T-cell leukemia/lymphoma).

  5. Selinexor - Wikipedia

    en.wikipedia.org/wiki/Selinexor

    Selinexor sold under the brand name Xpovio among others, is a selective inhibitor of nuclear export used as an anti-cancer medication.It works by blocking the action of exportin 1 [6] and thus blocking the transport of several proteins involved in cancer-cell growth from the cell nucleus to the cytoplasm, which ultimately arrests the cell cycle and leads to apoptosis. [8]

  6. He was just a toddler when he began difficult leukemia ... - AOL

    www.aol.com/just-toddler-began-difficult...

    After grueling treatments, he is cancer-free. In 2017, the Encalada family immigrated to the United States from Guayaquil, Ecuador in search of opportunities and a better life.

  7. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    Symptoms are sometimes treated surgically (splenectomy – removal of enlarged spleen) or by radiation therapy ("de-bulking" swollen lymph nodes). [citation needed] Initial CLL treatments vary depending on the exact diagnosis and the progression of the disease, and even with the preference and experience of the health care practitioner.

  8. Richter's transformation - Wikipedia

    en.wikipedia.org/wiki/Richter's_transformation

    Modern treatments and trials have improved the prognosis for almost all stages and types. Frequency: Rare. Some transformations are more common and/or more favorable than others. Progression to acute leukemia or severe lymphoma is rarer but does happen, though it can sometimes be treated.

  9. Leukemia - Wikipedia

    en.wikipedia.org/wiki/Leukemia

    Treatment may involve some combination of chemotherapy, radiation therapy, targeted therapy, and bone marrow transplant, with supportive and palliative care provided as needed. [3] [6] Certain types of leukemia may be managed with watchful waiting. [3] The success of treatment depends on the type of leukemia and the age of the person.

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