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  2. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.

  3. Melatonin - Wikipedia

    en.wikipedia.org/wiki/Melatonin

    Infobox references. Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

  4. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [5] The symptoms may include flu-like symptoms, trouble sleeping, nausea, poor balance ...

  5. Melatonin supplements can lull you to sleep on restless nights, but too much may lead to more rest disruption; here's what sleep experts say about proper dosage for adults and children.

  6. Seasonal affective disorder - Wikipedia

    en.wikipedia.org/wiki/Seasonal_affective_disorder

    Specialty. Psychiatry. Seasonal affective disorder (SAD) is a mood disorder subset in which people who typically have normal mental health throughout most of the year exhibit depressive symptoms at the same time each year. [1][2] It is commonly, but not always, associated with the reductions or increases in total daily sunlight hours that occur ...

  7. Ramelteon - Wikipedia

    en.wikipedia.org/wiki/Ramelteon

    Side effects of ramelteon include somnolence, dizziness, fatigue, nausea, exacerbated insomnia, and changes in hormone levels. [3] Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT 1 and MT 2 receptors. [3] The half-life and duration of ramelteon are much longer than those of melatonin. [7]

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  9. Insomnia - Wikipedia

    en.wikipedia.org/wiki/Insomnia

    Usage of melatonin as a treatment for insomnia in adults has increased from 0.4% between 1999 and 2000 to nearly 2.1% between 2017 and 2018. [163] While the use of melatonin in the short-term has been proven to be generally safe and it is shown to not be a dependent medication, side effects can still occur. [164]