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  2. Histidinemia - Wikipedia

    en.wikipedia.org/wiki/Histidinemia

    A typical characteristic of histidinemia is an increase in the blood histidine levels from normal levels (70–120 μM) to an elevated level (290–1420 μM). [3] Further testing includes: observing histidine as well as imidazolepyruvic acid metabolites in the urine. However, neonatal urine testing has been discontinued in most places, with the ...

  3. 3-Methylhistidine - Wikipedia

    en.wikipedia.org/wiki/3-Methylhistidine

    The normal concentration of 3-methylhistidine in the urine of healthy adult humans has been detected and quantified in a range of 3.63–69.27 micromoles per millimole (μmol/mmol) of creatinine, with most studies reporting the average urinary concentration between 15–20 μmol/mmol of creatinine. [1]

  4. Histidine ammonia-lyase - Wikipedia

    en.wikipedia.org/wiki/Histidine_ammonia-lyase

    Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. [5] The reaction is catalyzed by 3,5-dihydro-5-methyldiene-4 H -imidazol-4-one (MIO), an electrophilic cofactor which is formed autocatalytically by cyclization of the protein ...

  5. Histidine - Wikipedia

    en.wikipedia.org/wiki/Histidine

    Histidine (symbol His or H) [2] is an essential amino acid that is used in the biosynthesis of proteins.It contains an α-amino group (which is in the protonated –NH 3 + form under biological conditions), a carboxylic acid group (which is in the deprotonated –COO − form under biological conditions), and an imidazole side chain (which is partially protonated), classifying it as a ...

  6. Regina Kapeller-Adler - Wikipedia

    en.wikipedia.org/wiki/Regina_Kapeller-Adler

    Regina Kapeller-Adler, born Regina Kapeller, (28 June 1900 – 31 July 1991) was an Austrian biochemist who, in 1934, devised an innovative test for early pregnancy based on the detection of histidine in urine.

  7. Urocanic acid - Wikipedia

    en.wikipedia.org/wiki/Urocanic_acid

    Urocanic acid is found predominantly in the stratum corneum of the skin and it is likely that most of it is derived from filaggrin catabolism (a histidine-rich protein). When exposed to UVB irradiation, trans-urocanic acid is converted in vitro and in vivo to cis -urocanic acid (cis-UCA). [ 4 ]

  8. Urinalysis - Wikipedia

    en.wikipedia.org/wiki/Urinalysis

    Urinalysis, a portmanteau of the words urine and analysis, [1] is a panel of medical tests that includes physical (macroscopic) examination of the urine, chemical evaluation using urine test strips, and microscopic examination.

  9. Urine test strip - Wikipedia

    en.wikipedia.org/wiki/Urine_test_strip

    Automatic analysis of urine test strips using automated urine test strip analysers is a well-established practice in modern-day urinalysis. They can measure calcium , blood, glucose, bilirubin, urobilinogen, ketones, leukocytes, creatinine , microalbumin , pH, ascorbic acid and protein.