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  2. Selegiline - Wikipedia

    en.wikipedia.org/wiki/Selegiline

    [4] [8] Both standard clinical doses of oral selegiline (up to 10 mg/day) and higher doses of oral selegiline (e.g., 30 to 60 mg/day) have been used to treat depression, with the lower doses selectively inhibiting MAO-B and the higher doses producing dual inhibition of both MAO-A and MAO-B. [9] [24] Unlike oral selegiline, transdermal ...

  3. Pharmacology of selegiline - Wikipedia

    en.wikipedia.org/wiki/Pharmacology_of_selegiline

    [10] [9] It achieves blood levels of selegiline at a dose of 1.25 mg/day that are similar to those with conventional oral selegiline at a dose of 10 mg/day. [4] In addition, there is an at least 90% reduction in metabolites of selegiline including desmethylselegiline, levomethamphetamine, and levoamphetamine with the ODT formulation of ...

  4. Category:Selegiline - Wikipedia

    en.wikipedia.org/wiki/Category:Selegiline

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  5. Desmethylselegiline - Wikipedia

    en.wikipedia.org/wiki/Desmethylselegiline

    Selegiline and DMS were compared in a clinical study in which 10 mg of each drug was administered orally. [3] DMS showed 27-fold higher peak levels and 33-fold higher area-under-the-curve levels than selegiline in this study, suggesting that it has much greater oral bioavailability than selegiline. [3] Levoamphetamine is an active metabolite of ...

  6. Methylenedioxypropylaminopentane - Wikipedia

    en.wikipedia.org/wiki/Methylenedioxypropylamino...

    MPAP has comparable potency to PPAP and selegiline as a MAE in terms of enhancing the monoamine neurotransmitters in the isolated rat brain stem ex vivo. [1] However, it was 5-fold more potent than PPAP and selegiline as a MAE in rodents in vivo in terms of the minimum dose that significantly antagonized the behavioral depression induced by ...

  7. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]