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The mammillotegmental fasciculus emerges from the principal mammillary fasciculus of the mammillary body and travels dorsally together with the mammillothalamic tract before splitting off and turning caudally to enter the spinal column.
Axons divide within the gray matter; the thicker fibres form the MTT while the finer branches descend as the mammillotegmental fasciculus. [3] The MTT spreads fan-like as it terminates in the medial dorsal nucleus. [3] The axons from these nuclei form part of the thalamocortical radiations. [6]
Mammillotegmental fasciculus; References External links "Anatomy diagram: 13048.000-3". ... "Anatomy diagram: 13048.000-3". Roche Lexicon - illustrated navigator ...
Rostral interstitial nucleus of medial longitudinal fasciculus; Midbrain reticular formation; Dorsal raphe nucleus; Red nucleus; Ventral tegmental area. Parabrachial pigmented nucleus; Paranigral nucleus; Rostromedial tegmental nucleus; Caudal linear nucleus; Rostral linear nucleus of the raphe; Interfascicular nucleus; Substantia nigra. Pars ...
Diagram showing a few of the connections of afferent (sensory) fibers of the posterior root with the efferent fibers from the ventral column and with the various long ascending fasciculi. (Spinotectal fasciculus labeled at bottom right.)
It is located anterior and lateral to the medial longitudinal fasciculus. [citation needed] It is continuous caudally with the nucleus prepositus hypoglossi. [4] The PPRF (and adjacent regions of the pons) are traversed by fibers projecting to the abducens nucleus that mediate smooth pursuit, vestibular reflexes, and gaze holding. [5]: 498
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The medial forebrain bundle may serve as a target in treating treatment-resistant depression. [8] Since the MFB connects areas of the brain which are involved with motivated behavior, mood regulation, and antidepressant response the stimulation of the MFB through deep brain stimulation could be an effective form of treatment.