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A number of such organisms are currently being investigated for their use as treatment, including: Trichuris suis ova, [6] [7] commonly known as pig whipworm eggs; Necator americanus, [8] commonly known as hookworms; Trichuris trichiura ova, [9] commonly referred to as human whipworm eggs; and Hymenolepis diminuta, commonly known as rat tapeworm.
Trichuris trichiura, Trichocephalus trichiuris or whipworm, is a parasitic roundworm (a type of helminth) that causes trichuriasis (a type of helminthiasis which is one of the neglected tropical diseases) when it infects a human large intestine.
Trichuriasis, also known as whipworm infection, is an infection by the parasitic worm Trichuris trichiura (whipworm). [2] If the infection is only with a few worms, there are often no symptoms. [ 1 ] In those who are infected with many worms, there may be abdominal pain , fatigue and diarrhea . [ 1 ]
Trichuris suis is a whipworm; the variations in thickness of the anterior and posterior segments give the parasite the characteristic "whip-like" appearance. Adult females measure 6 to 8 cm and adult males 3 to 4 cm. T. suis eggs are oval (60 × 25 μm) and yellow-brown with bipolar plugs. [1] T. suis is also used in helminthic therapy studies. [2]
Mebendazole is given twice a day for three consecutive days, while albendazole is given as a single dose. WHO recommends annual treatment in areas where between 20 and 50% of people are infected, and a twice-a-year treatment if it is over 50%; and in low-risk situations (i.e. less than 20% prevalence) case-by-case treatment.
The frequency of egg deposition from an adult helminth is generally daily, and can occur up to six times per day for some Taenia species. Adult trematodes lay smaller numbers of eggs compared to cestodes or nematodes. However, the egg develops into a miracidia from which thousands of cercariae, or swimming larvae, develop.
It was in the 1950s that it was established that whipworms have direct life cycle, required no other animals (vectors or intermediate hosts for their transmission) and rather fragile eggs unlike most other helminths. [15] It is now known that all whipworm species have a similar general life cycle. [2] [24] Whipworm eggs are first ingested by ...
Trichuris serrata, commonly known as a whipworm, is a nematode of the genus Trichuris first discovered in domestic Brazilian cats by Dr. Otto Friedrich Bernhard von Linstow in 1879. [1] Since then, there have been reports of this species in North and South America, Australia, [ 2 ] and the Caribbean islands. [ 1 ]