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LEMS is often associated with lung cancer (50–70%), specifically small-cell carcinoma, [4] making LEMS a paraneoplastic syndrome. [5] Of the people with small-cell lung cancer, 1–3% have LEMS. [3] In most of these cases, LEMS is the first symptom of the lung cancer, and it is otherwise asymptomatic. [3]
IgG4-related disease (IgG4-RD), formerly known as IgG4-related systemic disease, is a chronic inflammatory condition characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, various degrees of fibrosis (scarring) and a usually prompt response to oral steroids.
Pulmonary symptoms may present early on, alongside other symptoms or they may manifest later in the progression of antisynthetase syndrome. [15] A recent study showed that pleural involvement is often associated with antisynthetase syndrome, reporting that 42.2% patients with antisynthetase syndrome had pleural effusions. [16]
Interstitial lung disease: Lungs Depends on the subtype (e.g. Anti-Jo1 in Anti-synthetase syndrome) Probable 31.5 per 100,000 (men), 26.1 per 100,000 (women) [85] Pulmonary alveolar proteinosis: Lungs Anti-GM-CSF antibodies Confirmed 6.2 per million [86] Rheumatoid lung disease: Lungs Rheumatoid factor, Anti-CCP antibodies Confirmed
It typically present as a painless, hard anterior neck mass, which progresses over weeks to years to produce symptoms of compression, including dysphagia, dyspnea choking and hoarseness. Patients may present with symptoms of hypothyroidism and hypoparathyroidism as the gland is replaced by Fibrous tissues .
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
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