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Ketamine, generally, stimulates breathing; however, in the first 2–3 minutes of a high-dose rapid intravenous injection, it may cause a transient respiratory depression. [73] At lower sub-anesthetic doses, psychiatric side effects are prominent. Most people feel strange, spacey, woozy, or a sense of floating, or have visual distortions or ...
The use of ketamine as an antidepressant has mainly been studied for the treatment of treatment-resistant depression(TRD). Single-dose use has been found to have noticeable and rapid anti-depressive effects that tend to last up to a week, accompanied by acute side-effects that resolve spontaneously. [22]
The high levels of ketamine found in his blood could cause "lethal effects" from cardiovascular overstimulation and respiratory depression, the Los Angeles County medical examiner said in a report.
Ketamine crystals on a glass plate. K-hole is the feeling of getting a high enough dose of ketamine to experience a state of dissociation.This intense detachment from reality is often a consequence of accidental overconsumption of ketamine; however, some users consciously seek out the k-hole as they find the powerful dissociative effects to be quite pleasurable and enlightening.
High doses may cause movement issues, body numbness, and slowed breathing. What are signs of a ketamine overdose? Potential side effects of an overdose include respiratory failure and death.
When used at high doses, ketamine can cause bladder damage, sometimes seen in people who use the drug recreationally. Far less is known about the neurological effects of long-term use.
(CNN) — Matthew Perry’s 2023 death from what the Los Angeles County medical examiner’s office determined were “the acute effects of ketamine” cast a shadow over a medication that has ...
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
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