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Zinc L-carnosine (beta-alanyl-L-histidinato zinc [1]) (N-(3-aminopropionyl)-L-histidinato zinc [2]), often simply called zinc carnosine, and also known as polaprezinc, [3] is a mucosal protective [4] [5] chelate compound of zinc and L-carnosine invented by Hamari Chemicals, Ltd. [6] [7] It is a quadridentate 1:1 complex of a polymeric nature. [6]
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. [1] Chelation therapy has a long history of use in clinical toxicology [2] and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of ...
The most common side effect seen is constipation (2–3%). Less commonly reported side effects (<0.5%) include flatulence, headache, hypophosphatemia, xerostomia (dry mouth), and bezoar formation. [24] [25] [26] Use of this drug is not recommended for people with chronic kidney failure, as it might cause aluminium accumulation and toxicity.
The side effects of too much zinc . As the idiom goes, “too much of a good thing” isn't always good. Some side effects of excessive zinc intake include gastrointestinal symptoms (nausea ...
Carnosine is naturally produced by the body in the liver [2] from beta-alanine and histidine. Like carnitine, carnosine is composed of the root word carn, meaning "flesh", alluding to its prevalence in meat. [3] There are no plant-based sources of carnosine. [4] Carnosine is readily available as a synthetic nutritional supplement.
Side effects may include abdominal pain, vomiting, headache, and feeling tired. [2] While normal doses are deemed safe in pregnancy and breastfeeding, the safety of larger doses is unclear. [3] Greater care should be taken in those with kidney problems. [2] Zinc is an essential mineral in people as well as other animals. [4]