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Methylene blue is employed as a medication for the treatment of methemoglobinemia, which can arise from ingestion of certain pharmaceuticals, toxins, or broad beans in those susceptible. [11] Normally, through the NADH - or NADPH -dependent methemoglobin reductase enzymes, methemoglobin is reduced back to hemoglobin.
Methylene blue is given as a 1% solution (10 mg/ml) 1 to 2 mg/kg administered intravenously slowly over five minutes. Although the response is usually rapid, the dose may be repeated in one hour if the level of methemoglobin is still high one hour after the initial infusion. Methylene blue inhibits monoamine oxidase, and serotonin toxicity can ...
The methylene blue allows the methaemoglobin to be converted to haemoglobin. Supportive treatment is also usually provided, depending on the severity of the toxicity, that resulted in the anaemia. [11] Ascorbic acid is used to treat methemoglobinemia, a symptom of naphthalene poisoning and is used when methylene blue is not available, or in ...
While many different things can cause diarrhea—including infections or a more serious gastrointestinal condition—in most cases, it will go away after a few days without the need for treatment.
Infection symptoms and signs include bloody diarrhea, stomach cramps, vomiting and occasionally, fever. The bacteria can also cause pneumonia, other respiratory illnesses and urinary tract infections. [10] [11] An easy way to differentiate between different types of coliform bacteria is by using an eosin methylene blue agar plate. [12]
Eosin methylene blue (EMB, also known as "Levine's formulation") is a selective and differential media used for the identification of Gram-negative bacteria, [1] specifically the Enterobacteriaceae. EMB inhibits the growth of most Gram-positive bacteria. EMB is often used to confirm the presence of coliforms in a sample.
Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. It is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates, which are examined under a light microscope.
Allergic-like reactions and methemoglobinemia have been documented after the use of methylene blue dye in chromopertubation. [9] These reported symptoms vary from blue discoloration of body fluids to anaphylactic shock. [10] Methemoglobinemia is a blood disorder that can potentially result in various levels of cyanosis. [11]