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Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.
Like many autoimmune diseases, SPS exists on a spectrum and, as a result, symptoms can look quite different in different people, Dr. Scott Newsome, head of the Johns Hopkins Stiff Person Syndrome ...
Symptoms of stiff person syndrome typically begin in the upper body, according to the Cleveland Clinic. As it progresses, symptoms typically move to the lower body, making it difficult to walk and ...
Classic stiff person syndrome: symptoms include muscle stiffness, rigidity, and spasms. Focal stiff person syndrome: similar to the classic syndrome but may be isolated to an arm or leg ...
Stiff-person syndrome, aka Moersch-Woltman syndrome, is a neurological disorder that can cause symptoms such as stiffening in the muscles of the trunk, along with stiffness and rigidity in the ...
There is no cure for stiff person syndrome but its symptoms can be treated, according to the National Institutes of Health. The doctors at Johns Hopkins developed a plan for Allen-Kulyk that ...
Restless legs syndrome: Central nervous system (thought to involve dopaminergic pathways) Unknown Uncertain 5-15% (more common in older adults) [67] Stiff-person syndrome: Central nervous system Anti-GAD, anti-amphiphysin Confirmed Rare [68] Sydenham's chorea: Brain Anti-basal ganglia Confirmed Rare (linked to Group A streptococcal infection) [69]
What is stiff person syndrome? Stiff person syndrome is a rare autoimmune neurological condition that affects the central nervous system, causing painful spasms and muscle rigidity. These symptoms ...