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Similar considerations apply to the submandibular gland, but xerostomia is less common if only one parotid gland is included in the radiated field [145] and the contralateral submandibular gland is spared (less than 39 Gy) [146] In the same manner, the radiation dose to the pharyngeal constrictor muscles, larynx, and cricopharyngeal inlet ...
Mucoepidermoid carcinoma (MEC) [1] is the most common type of minor salivary gland malignancy in adults. Mucoepidermoid carcinoma can also be found in other organs, such as bronchi, lacrimal sac, [2] and thyroid gland. Mucicarmine staining is one stain used by pathologist for detection. [3]
Prognosis is good for acinic cell carcinoma of the parotid gland, with five-year survival rates approaching 90%, and 20-year survival exceeding 50%. Patients with acinic cell carcinomas with high grade transformation (sometimes also called dedifferentiation ) have significantly worse survival.
Little is known about the total incidence of salivary gland tumours as most benign tumours go unrecorded in national cancer registries. [2] The majority of salivary tumours are benign (65-70%). [3] Within the parotid gland 75 - 80% of tumours are benign. Around 50% of the tumours found in the submandibular glands are benign.
Head and neck cancer is a general term encompassing multiple cancers that can develop in the head and neck region. These include cancers of the mouth, tongue, gums and lips (oral cancer), voice box (), throat (nasopharyngeal, oropharyngeal, [1] hypopharyngeal), salivary glands, nose and sinuses.
In the United States there has been an increase in the 5-year relative survival rate between people diagnosed with cancer in 1975-1977 (48.9%) and people diagnosed with cancer in 2007-2013 (69.2%); these figures coincide with a 20% decrease in cancer mortality from 1950 to 2014. [8]
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