Search results
Results From The WOW.Com Content Network
Spermatogenesis is controlled by androgens, namely testosterone and follicle-stimulating hormone (FSH), these are the most important androgens that control the process. FSH uses very specific G-coupled receptors that can be found only on Sertoli cells, this hormone is secreted by the pituitary gland, located in the brain.
The testicles are two gonads that produce sperm by meiotic division of germ cells within the seminiferous tubules, [1] and synthesize and secrete androgens that regulate the male reproductive functions. The site of production of androgens is the Leydig cells that are located in the interstitium between seminiferous tubules. [1]
Levels of estrogen that are too high can be detrimental to spermatogenesis due to suppression of gonadotropin secretion and by extension intratesticular testosterone production. [35] The connection between spermatogenesis and prolactin levels appears to be moderate, with optimal prolactin levels reflecting efficient sperm production. [28] [36]
Androgenesis is a system of asexual reproduction that requires the presence of eggs and occurs when a zygote is produced with only paternal nuclear genes.During standard sexual reproduction, one female parent and one male parent each produce haploid gametes (such as a sperm or egg cell, each containing only a single set of chromosomes), which recombine to create offspring with genetic material ...
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
Throughout adulthood, androgens and FSH cooperatively act on Sertoli cells in the testes to support sperm production. [10] Exogenous androgen supplements can be used as a male contraceptive. Elevated androgen levels caused by use of androgen supplements can inhibit production of LH and block production of endogenous androgens by Leydig cells.
This response mechanism plays a crucial role in male sexual differentiation and puberty, as well as other tissue types and processes, such as the prostate gland (regulate secretory functions), hair follicles (androgens influence hair growth patterns), skin (androgens regulate sebum production and the thickening and maturation of the skin), and ...
XY differences of sex development – Atypical androgen production or inadequate androgen response, which can cause incomplete masculinization in XY males. Varies from mild failure of masculinization with undescended testes to complete sex reversal and female phenotype (Androgen insensitivity syndrome) Swyer syndrome.