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NAION presents as a painless loss of vision, often when awakening, that occurs over hours to days. Most patients lose the lower half of their visual field (an inferior altitudinal loss), though superior altitudinal loss is also common. The pathophysiology of NAION is unknown, but it is related to poor circulation in the optic nerve head.
The most frequent presenting signs and symptoms of primary CNS vasculitis were focal neurological defecits (seen in 63% of cases), headaches (51%) and cognitive impairment (41%). [4] Other presenting symptoms include aphasia or other difficulties with speech (35-43%), ataxia , visual field deficits, acute or subacute encephalopathy (which may ...
Older people may have poor balance, difficulty controlling urination, or mental impairment. [4] In babies, there may be a rapid increase in head size. Other symptoms may include vomiting, sleepiness, seizures, and downward pointing of the eyes. [1] Hydrocephalus can occur due to birth defects (primary) or can develop later in life (secondary). [1]
Vertebrobasilar insufficiency (VBI) describes a temporary set of symptoms due to decreased blood flow in the posterior circulation of the brain.The posterior circulation supplies the medulla, pons, midbrain, cerebellum and (in 70-80% of people) supplies the posterior cerebellar artery to the thalamus and occipital cortex. [1]
When the low cerebral blood flow persists for a longer duration, this may develop into an infarction in the border zones (areas of poor blood flow between the major cerebral artery distributions). In more severe instances, global hypoxia-ischemia causes widespread brain injury leading to a severe cognitive sequelae called hypoxic-ischemic ...
An online survey conducted by the Cleveland Clinic of 1,174 men 18 years or older, found that 72% of men would rather do household tasks, such as cleaning the bathroom or mowing the lawn, than see ...
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.
The prevalence of PAD in the general population is 3–7%, affecting up to 20% of those over 70; [85] 70%–80% of affected individuals are asymptomatic; only a minority ever require revascularization or amputation. [citation needed] Peripheral artery disease affects one in three diabetics over the age of 50. In the US, it affects 12–20 ...