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  2. Hypereosinophilic syndrome - Wikipedia

    en.wikipedia.org/wiki/Hypereosinophilic_syndrome

    Depending on eosinophil target-organ infiltration, the clinical presentation of hypereosinophilic syndrome (HES) varies from patient to patient. [13] Individuals with myeloproliferative variant HES may be more likely to experience mucosal ulcerations involving the genitalia or airways, while patients with lymphocytic variant HES typically exhibit prominent skin symptoms such as urticarial ...

  3. Eosinophilic myocarditis - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic_myocarditis

    The specific treatment (i.e. treatment other than measures to support the cardiovascular system) of eosinophilic myocarditis differs from the specific treatment of other forms of myocarditis in that it is focused on relieving the underlying reason for the excessively high numbers and hyperactivity of eosinophils as well as on inhibiting the ...

  4. Eosinophilia - Wikipedia

    en.wikipedia.org/wiki/Eosinophilia

    Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds 5 × 10 8 /L (500/μL). [1] Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 1.5 × 10 9 /L (i.e. 1,500/μL).

  5. Eosinophil cationic protein - Wikipedia

    en.wikipedia.org/wiki/Eosinophil_cationic_protein

    Eosinophil cationic protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. [4] In humans, the eosinophil cationic protein is encoded by the RNASE3 gene. [5] ECP is released during degranulation of eosinophils. This protein is related to inflammation and asthma because in these cases, there are ...

  6. Eosinophil - Wikipedia

    en.wikipedia.org/wiki/Eosinophil

    [30] [31] Mepolizumab and benralizumab are other treatment options that target the alpha subunit of the IL-5 receptor, thereby inhibiting its function and reducing the number of developing eosinophils as well as the number of eosinophils leading to inflammation through antibody-dependent cell-mediated cytotoxicity and eosinophilic apoptosis.

  7. Eosinophilic bronchitis - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic_bronchitis

    Eosinophilic bronchitis (EB) is a type of airway inflammation due to excessive mast cell recruitment and activation in the superficial airways as opposed to the smooth muscles of the airways as seen in asthma. [1] [2] It often results in a chronic cough. [1] Lung function tests are usually normal. [1] Inhaled corticosteroids are often an ...

  8. Lymphocyte-variant hypereosinophilia - Wikipedia

    en.wikipedia.org/wiki/Lymphocyte-variant_hyper...

    In 1987, however, a 42-year-old male patient was described who presented with cardiac failure, mitral heart valve regurgitation, pericardial effusion, splenomegaly, kidney dysfunction, non-specific skin lesions, a six-year history of eosinophilia, and, on admission, an eosinophil blood count of 7,150 per microliter (normal <500/microliter), a ...

  9. Eosinophilic esophagitis - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic_esophagitis

    A minimum of 15 eosinophils per high-power field are required to make the diagnosis. Eosinophilic inflammation is not limited to the esophagus alone and does extend through the whole gastrointestinal tract. Profoundly degranulated eosinophils may also be present, as may micro-abscesses and an expansion of the basal layer. [3] [10]

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