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Within the penicillin class, pivmecillinam is considered the first-line empiric treatment for acute cystitis due to its wide spectrum of activity against gram-negative bacteria and its specific efficacy in the urinary tract. It has consistently demonstrated a high cure rate of over 85% for UTIs and a low resistance rate among E. coli strains.
Lower urinary tract infections may involve the bladder (cystitis) or urethra while upper urinary tract infections affect the kidney (pyelonephritis). [10] Symptoms from a lower urinary tract infection include suprapubic pain, painful urination ( dysuria ), frequency and urgency of urination despite having an empty bladder. [ 1 ]
Uses of nitrofurantoin include the treatment of uncomplicated urinary tract infections (UTIs) and prophylaxis against UTIs in people prone to recurrent UTIs. [9] It is a first-line therapy for acute uncomplicated cystitis. [21] It is not recommended for empiric treatment of hospital-acquired UTIs. [21]
595 Cystitis. 595.0 Cystitis, acute; 595.1 Cystitis, interstitial, chronic. 595.82 Cystitis, irradiation; 596 Other disorders of bladder. 596.0 Bladder neck obstruction; 596.4 Atony of bladder; 596.5 Other functional disorders of bladder. 596.51 Bladder hypertonicity; 596.52 Bladder compliance, low; 596.54 Neurogenic bladder, NOS; 596.55 ...
Meningitis, MRSA, topical use, or for low-cost internal treatment. Historic: typhus, cholera. Gram-negative, Gram-positive, anaerobes: Rarely: aplastic anemia. Inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome Fosfomycin: Monurol, Monuril: Acute cystitis in women
It is a definitive treatment against susceptible extended-spectrum β-lactamase (ESBL)-producing Gram-negative bacteria. [15] The drug is not effective against Pseudomonas aeruginosa , Morganella morganii , or Providencia stuartii , nor against AmpC β-lactamase - and ESBL-producing Gram-negative bacteria or carbapenem-resistant ...